George Payne may refer to:
George Payne (Freemason) (1685-1757),
George Payne (racehorse owner) (1804-1878),
George Payne (baseball) (1889-1959), American baseball pitcher and member of the Texas League Hall of Fame,
George Payne (footballer) (1921-1987), English footballer who played as a goalkeeper for Tranmere Rovers and Northwich Victoria,
George Payne (footballer born 1887) (1887-1932), former Tottenham Hotspur, Crystal Palace and Sunderland player,
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