Sugarland will perform with Melissa Etheridge during the finale of the Stand Up to Cancer event in Los Angeles on Friday (Sept. 5). The special will air live on ABC, CBS and NBC starting at 8 p.m. ET/PT. As previously announced, the show will also feature performances from LeAnn Rimes and Carrie Underwood. Money raised from the projects benefit Stand Up to Cancer (SU2C), an organization dedicated to accelerating ground-breaking cancer research.