Jewel will take Harris' place at the tour's two Oregon dates -- June 10 in Troutdale and June 11 in Bend.
The tour's name reflects the title of Mellencamp's 23rd full-length album, Sad Clowns & Hillbillies, set for release on March 28 on Republic Records. Every online ticket purchased for the tour comes with one CD copy of the album.
Carter, who previously toured with Mellencamp on his Plain Spoken Tour, is featured on his new album. She is the daughter of the late June Carter Cash and Country Music Hall of Fame member Carl Smith.
Tickets for the tour will be available to the general public beginning Feb. 24. For more information, visit Mellencamp.com.
Here's a list of the confirmed tour dates:
June 5: Denver (Fiddler's Green Amphitheatre)
June 7: Boise, Idaho (Outlaw Field at the Idaho Botanical Garden)
June 8: Redmond, Washington (Marymoor Park)
June 10: Troutdale, Oregon (McMenamins Edgefield)
June 11: Bend, Oregon (Les Schwab Amphitheater)
June 13-14: Saratoga, California (The Mountain Winery)
June 17: Murphys, California (Ironstone Amphitheatre)
June 18: Los Angeles, (Greek Theatre)
June 21: Grand Prairie, Texas (Verizon Theatre)
June 22: Sugar Land, Texas (Smart Financial Centre at Sugar Land)
June 24: St. Augustine, Florida (St. Augustine Amphitheatre)
June 25: Boca Raton, Florida (Mizner Park Amphitheater)
June 27: Atlanta (Chastain Park Amphitheatre)
June 28: Cary, North Carolina (Cary's Booth Amphitheatre)
June 30: Gilford, New Hampshire (Bank of New Hampshire Pavilion)
July 1: Lenox, Massachusetts (Tanglewood)
July 3: Vienna, Virginia (Wolf Trap)
July 6: Philadelphia (The Mann)
July 7: Bethel, NY (Bethel Woods Center for the Arts)
July 8: Canandaigua, New York (CMAC)
July 11: Queens, New York (Forest Hills Stadium)